Cohort study to evaluate the effect of vitamin D, magnesium, and vitamin B 12 in combination on progression to severe outcomes in older patients with coronavirus (COVID-19)
Chuen Wen Tan 1, Liam Pock Ho 2, Shirin Kalimuddin 3, Benjamin Pei Zhi Cherng 4, Yii Ean Teh 4, Siew Yee Thien 4, Hei Man Wong 4, Paul Jie Wen Tern 4, Manju Chandran 5, Jason Wai Mun Chay 6, Chandramouli Nagarajan 1, Rehena Sultana 7, Jenny Guek Hong Low 3, Heng Joo Ng 8
Conclusions: A vitamin D / magnesium / vitamin B12 combination in older COVID-19 patients was associated with a significant reduction in the proportion of patients with clinical deterioration requiring oxygen support, intensive care support, or both. This study supports further larger randomized controlled trials to ascertain the full benefit of this combination in ameliorating the severity of COVID-19.
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